Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 4-hydroxy-3-[1-(4-nitrophenyl-2,3,5,6-d4)-3-oxobutyl]-2H-1-benzopyran-2-one
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C19H11D4NO6
Formula Weight: 357.4
CAS Number: 2937878-24-3
Notes: Acenocoumarol-d4 is intended for use as an internal standard for the quantification of acenocoumarol (Item No. 10010569) by GC- or LC-MS. Acenocoumarol is an anticoagulant and vitamin K antagonist.{45456} It inhibits the reduction of vitamin K1 epoxide to vitamin K1 by vitamin K1 epoxide reductase (VKOR;IC50 = 1.5 and 5.8 nM for VKORC1 and VKORC1L1, respectively).{45456} Acenocoumarol also inhibits a variety of VKOR mutants in cell-based reporter assays (IC50s = 0.54-11.21 nM).{61088} It prolongs prothrombin time in rat blood when administered at a dose of 1.5 mg/kg.{60915}
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