Acetylethylcholine mustard (hydrochloride), CAS 103994-00-9

Acetylethylcholine mustard (hydrochloride), CAS 103994-00-9
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MEXHY-124892A-0
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MedChemExpress

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Product Description: Acetylethylcholine mustard hydrochloride (Acetyl-AF64) is an inhibitor of choline acetyl-transferase that reduces the contraction frequency of the myotubes by inhibiting the synthesis of acetylethylcholine (Ach) with the half-maximal inhibitory concentration (IC50) of 1.22 mM. Acetylethylcholine mustard hydrochloride is an irreversible ligand for the high affinity choline transport system. Acetylethylcholine mustard hydrochloride is also a cholinotoxin. Acetylethylcholine mustard hydrochloride is a precursor for ethylcholine mustard aziridinium ion[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C8H17Cl2NO2

References: [1]Charoensook SN, et al. Bioreactor model of neuromuscular junction with electrical stimulation for pharmacological potency testing. Integr Biol (Camb). 2017 Dec 11;9(12):956-967. /[2]Sutalangka C, et al. Laser acupuncture improves memory impairment in an animal model of Alzheimer's disease. J Acupunct Meridian Stud. 2013 Oct;6(5):247-51.

CAS Number: 103994-00-9

Molecular Weight: 230.13

Research Area: Neurological Disease

Target: Histone Acetyltransferase
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SKU MEXHY-124892A-0
Manufacturer MedChemExpress
Manufacturer SKU HY-124892A-0
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