Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (3R)-3-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane, monobromide
Purity: ≥95%
Formula Markup: C26H30NO4S2 / Br
Formula Weight: 564.6
CAS Number: 320345-99-1
Notes: Aclidinium is an antagonist of muscarinic acetylcholine receptors (mAChRs; Kis = 0.1, 0.14, 0.14, 0.21, and 0.16 for the M1-M5 receptors, respectively).{34049} It induces relaxation of precontracted isolated human bronchi when used at a concentration of 0.1 µM.{61751} Aclidinium reduces bronchoconstriction induced by ACh (Item No. 23829) in anesthetized guinea pigs when administered via nebulization.{34049} Formulations containing aclidinium have been used in the treatment of chronic obstructive pulmonary disease (COPD).