Acoltremon, CAS 68489-09-8

Product Description: Acoltremon (WS-12; AR-15512) is a potent and selective TRPM8 agonist, the menthol derivative, as a cooling agent. Acoltremon shows analgesic effect, and can be used in chronic neuropathic pain research[1][2].

Applications: Cancer-programmed cell death

Formula: C18H27NO2

References: [1]Beck B, et al. Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators. Cell Calcium. 2007 Mar;41(3):285-94./[2]Ma S, et al. Menthol derivative WS-12 selectively activates transient receptor potential melastatin-8 (TRPM8) ion channels. Pak J Pharm Sci. 2008 Oct;21(4):370-8.

CAS Number: 68489-09-8

Molecular Weight: 289.41

Compound Purity: 99.13

Research Area: Cancer

Solubility: DMSO : 20 mg/mL (ultrasonic)

Target: TRP Channel

• SKU: MEXHY-108449-500
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108449-500
• Package Unit: 500 mg
• Quantity Unit: STK