Clone Name: 7H12
Application Note: WB: 1:500 - 1:1000. ICC/IF: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 84
Specificity/Sensitivity: Weak cross reactivity is observed to ADMA9 and ADMA15 in western blotting.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 500 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature enzyme that is involved in the proteolytic release of membrane-bound proteins in a process called ectodomain shedding. Mice lacking the encoded protein die in utero with multiple defects of the developing central nervous system, somites, and cardiovascular system. [provided by RefSeq, May 2016]
Uniprot ID: O35598
Antigen Species: Mouse
Immunogen: Mouse recombinant protein of ADAM10 ectodomain
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: a disintegrin and metallopeptidase domain 10
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