Target Synonym: A disintegrin and metalloproteinase with thrombospondin motifs 2;A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 2;ADAM metallopeptidase with thrombospondin type 1 motif 2;ADAM TS 2;ADAM TS2;ADAM-TS 2;ADAM-TS2;ADAMTS 3;ADAMTS-2;ADAMTS2;ATS2;EC 3.4.24.14;EDS VIIB;EDS VIIC;hPCPNI;NPI;PC I NP;PC I-NP;PCINP;PCPNI;pNPI;Procollagen I N proteinase;Procollagen I N-proteinase;Procollagen I/II amino propeptide processing enzyme;Procollagen I/II amino propeptide-processing enzyme;Procollagen N endopeptidase;Procollagen N-endopeptidase
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants.
Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Immunogen: Synthetic peptide of human ADAMTS2
Dilution: IHC 1:30-1:150
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