Product Description: Adefovir dipivoxil (Standard) is the analytical standard of Adefovir dipivoxil. This product is intended for research and analytical applications. Adefovir dipivoxil is an orally active adenosine analog and Adefovir prodrug. Adefovir dipivoxil inhibits DNA synthesis, activates the ATR signaling pathway, and disrupts the KCTD12-CDK1 interaction. Adefovir dipivoxil has antiviral activity against PRV, HBV, and orthopoxviruses. Adefovir dipivoxil has inhibitory effects on both lamivudine-resistant and wild-type strains. Adefovir dipivoxil has antitumor activity against lung and colon cancer[1][2][3][4][5][6][7][8][9][10][11].
Formula: C20H32N5O8P
References: [1]Noble S, et al. Adefovir dipivoxil. Drugs. 1999;58(3):479-489./[2]Buti M, et al. Adefovir dipivoxil. Drugs Today (Barc). 2003;39(2):127-135./[3]Mark N Prichard, et al. Orthopoxvirus targets for the development of antiviral therapies. Curr Drug Targets Infect Disord. 2005 Mar;5(1):17-28.
CAS Number: 142340-99-6
Molecular Weight: 501.47
Research Area: Infection; Cancer
Target: Endogenous Metabolite;HBV;Orthopoxvirus;Reference Standards;Reverse Transcriptase
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