Product Description: ADX71441 is a potent and selective positive allosteric modulator of the GABAB receptor. ADX71441 is bioavailable after oral administration and is brain penetrant. ADX71441 has the potential for research of anxiety, pain and spasticity[1].
Applications: Neuroscience-Neuromodulation
Formula: C19H15ClF2N4O4
References: [1] Kalinichev M, et al. The drug candidate, ADX71441, is a novel, potent and selective positive allosteric modulator of the GABAB receptor with a potential for treatment of anxiety, pain and spasticity. Neuropharmacology. 2017;114:34-47.
CAS Number: 1207440-88-7
Molecular Weight: 436.80
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: GABA Receptor