AEE788, CAS 497839-62-0

Product Description: AEE788 is an inhibitor of the EGFR and ErbB2 with IC50 values of 2 and 6 nM, respectively.

Applications: Cancer-Kinase/protease

Formula: C27H32N6

References: [1]Traxler P, et al. AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity. Cancer Res. 2004 Jul 15;64(14):4931-4941./[2]Park et al. AEE788, a dual tyrosine kinase receptor inhibitor, induces endothelial cell apoptosis in human cutaneous squamous cell carcinoma xenografts in nude mice. Clin Cancer Res. 2005 Mar 1;11(5):1963-1973.

CAS Number: 497839-62-0

Molecular Weight: 440.58

Compound Purity: 99.13

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Apoptosis;EGFR

• SKU: MEXHY-10045-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10045-25
• Package Unit: 25 mg
• Quantity Unit: STK