AF/LE Purified Anti-Mouse CD105 Antibody(MJ7/18)

Target Synonym: HHT;ORW1;AI528660;AI662476;CD105;END;Endo;Endoglin;HHT1;ORW;S-endoglin;Edg;Eng;END;HHT1;ORW;ORW1;CD 105;CD105 antigen;EGLN;FLJ41744;Osler Rendu Weber syndrome 1;RP11 228B15.2;SN6

Background: Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.

Immunogen: Recombinant Human CD105 protein

Buffer: Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Dilution: FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

• SKU: ELSE-AB-F12330-25
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-F12330-25
• Package Unit: 25μg
• Quantity Unit: STK
• Reactivity: Mouse (Murine)
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rat IgG2a κ
• Host: Rat
• Conjugate: Unconjugated