AG-636, CAS 1623416-31-8

Product Description: AG-636 is a potent, reversible, selective and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 17 nM. AG-636 has strong anticancer effects[1].

Applications: Cancer-programmed cell death

Formula: C21H17N3O2

References: [1]Gabrielle McDonald, et al. Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate Dehydrogenase. Mol Cancer Ther. 2020 Dec;19(12):2502-2515.

CAS Number: 1623416-31-8

Molecular Weight: 343.38

Compound Purity: 98.25

Research Area: Cancer

Solubility: DMSO : 31.25 mg/mL (ultrasonic)

Target: Dihydroorotate Dehydrogenase;DNA/RNA Synthesis

• SKU: MEXHY-137463-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-137463-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK