AGI-5198, CAS 1355326-35-0

Product Description: AGI-5198 (IDH-C35) is a potent and selective mutant IDH1R132H inhibitor with an IC50 of 0.07 μM.

Applications: Cancer-programmed cell death

Formula: C27H31FN4O2

References: [1]Rohle D, et al. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science. 2013 May 3;340(6132):626-30./[2]Molenaar RJ, et al. Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198. Cancer Res. 2015 Nov 15;75(22):4790-802.

CAS Number: 1355326-35-0

Molecular Weight: 462.56

Compound Purity: 99.77

Research Area: Cancer

Solubility: DMF : ≥ 50 mg/mL/DMSO : 20.83 mg/mL (ultrasonic)

Target: Isocitrate Dehydrogenase (IDH)

• SKU: MEXHY-18082-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18082-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK