AGS-16C3F

Product Description: AGS-16C3F is an antibody-drug conjugate (ADC) targeting ENPP3. AGS-16C3F is composed of ENPP3-targeting Anti-ENPP3/CD203c Antibody (HY-P990315) linked to Monomethyl auristatin F (HY-15579) via a linker. AGS-16C3F has anti-tumor activity and can be used in the study of metastatic renal cell carcinoma (mRCC)[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Kollmannsberger C, et al. A Randomized Phase II Study of AGS-16C3F Versus Axitinib in Previously Treated Patients with Metastatic Renal Cell Carcinoma. Oncologist. 2021 Mar;26(3):182-e361./[2]Zhang Y, et al. In vitro and in vivo efficacy of an anti-CD203c conjugated antibody (AGS-16C3F) in mouse models of advanced systemic mastocytosis. Blood Adv. 2019 Feb 26;3(4):633-643.

Molecular Weight: N/A

Research Area: Cancer

Target: Antibody-Drug Conjugates (ADCs);Phosphodiesterase (PDE)

• SKU: MEXHY-171544-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-171544-0
• Package Unit: Get quote
• Quantity Unit: STK