AHR agonist 3, CAS 23749-58-8

Product Description: AHR agonist 3 is an aryl hydrocarbon receptor (AhR) agonist, that can induces cell cycle arrest or apoptosis via activation of tumor-suppressive transcriptional programs. AHR agonist 3 inhibits triple-negative breast cancer (TNBC) stem cell growth via AhR while exhibits minimal cytotoxicity against normal human primary cells and can be used for cancer research[1].

Applications: Cancer-programmed cell death

Formula: C18H10N2O

References: [1]Elson DJ, et.al. Induction of Aryl Hydrocarbon Receptor-Mediated Cancer Cell-Selective Apoptosis in Triple-Negative Breast Cancer Cells by a High-Affinity Benzimidazoisoquinoline. ACS Pharmacol Transl Sci. 2023 Jun 7;6(7):1028-1042.

CAS Number: 23749-58-8

Molecular Weight: 270.28

Compound Purity: 99.79

Research Area: Cancer

Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Apoptosis;Aryl Hydrocarbon Receptor

• SKU: MEXHY-W338764-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W338764-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK