AIRE (isoform 1) blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89336.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Background: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]

Region Sequence: C-KDVDLSQPRKGRKP

Full Name: autoimmune regulator

• SKU: GTX89336-PEP-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX89336-PEP-100
• Package Unit: 100 μg
• Quantity Unit: STK
• Human Gene ID: 326