AKI603, CAS 1432515-73-5

Description: AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2].

CAS Number: 1432515-73-5

Formula: C19H23N9O2

Molecular Weight: 409,45

References: Le-Xun Wang, et al. Aurora A Kinase Inhibitor AKI603 Induces Cellular Senescence in Chronic Myeloid Leukemia Cells Harboring T315I Mutation. Sci Rep. 2016 Nov 8;6:35533.

• SKU: TGMT64338-1mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T64338-1mg
• Package Unit: 1 mg
• Quantity Unit: STK