Alectinib analog, CAS 1256577-71-5

Product Description: Alectinib analog (CH5424802 analog) is a selective ALK inhibitor with activity in blocking resistance gating mutations. The synthetic optimization of alectinib analog allows it to be combined with specific peptides to improve the ability to target cancer cells. Alectinib analog exhibits low micromolar IC50 values in antiproliferation and shows good cytotoxic effects. The inhibitory activity of alectinib analog is closely related to its stability and release of active ingredients. Alectinib analog demonstrated the ability to inhibit vascular septal length or width in an in vivo zebrafish model[1].

Applications: Cancer-Kinase/protease

Formula: C28H30N4O2

References: [1]Synthesis and Anti-Angiogenic Activity of Novel c(RGDyK) Peptide-Based JH-VII-139-1 Conjugates

CAS Number: 1256577-71-5

Molecular Weight: 454.56

Research Area: cancer

Target: Anaplastic lymphoma kinase (ALK)

• SKU: MEXHY-W814315-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W814315-50
• Package Unit: 50 mg
• Quantity Unit: STK