Product Description: Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties[1]. Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China[2]. Aloperine induces apoptosis and autophagy in HL-60 cells[1].
Applications: Neuroscience-Neurodegeneration
Formula: C15H24N2
References: [1]Lin Z, et al. In vitro anti-tumour activities of quinolizidine alkaloids derived from Sophora flavescens Ait. Basic Clin Pharmacol Toxicol. 2011 May;108(5):304-9./[2]Yuan XY, et al. Effects and mechanisms of aloperine on 2, 4-dinitrofluorobenzene-induced allergic contact dermatitis in BALB/c mice. Eur J Pharmacol. 2010 Mar 10;629(1-3):147-52.
CAS Number: 56293-29-9
Molecular Weight: 232.371
Compound Purity: 98.0
Research Area: Cancer; Infection; Inflammation/Immunology
Solubility: DMSO : 5.56 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Apoptosis;Autophagy;Filovirus;HIV
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