Product Description: AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.
Applications: COVID-19-immunoregulation
Formula: C27H27F3N2O4
References: [1]Bain G, et al. Pharmacology of AM211, a potent and selective prostaglandin D2 receptor type 2 antagonist that is active in animal models of allergic inflammation. J Pharmacol Exp Ther. 2011 Jul;338(1):290-301.
CAS Number: 1175526-27-8
Molecular Weight: 500.51
Compound Purity: 98.79
Research Area: Inflammation/Immunology; Endocrinology
Solubility: DMSO : ≥ 125 mg/mL
Target: Prostaglandin Receptor