AM281, CAS 202463-68-1

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide

Purity: ≥98%

Formula Markup: C21H19Cl2IN4O2

Formula Weight: 557.2

CAS Number: 202463-68-1

Notes: AM281 is a potent and selective central cannabinoid (CB1) receptor antagonist/inverse agonist (Kis = 12 nM and 4,200 nM for CB1 and CB2, respectively).{13046,21749} Structurally, it is an analog of the CB1 inverse agonist rimonabant (Item No. 9000484).{21749} It has no effect on the vanilloid TRPV1 receptor.{12165} AM281 has been used to evaluate the potential effects of compounds at CB1.{13244,21496} It has also been used to study the membrane localization and cycling of CB1.{13567}

• SKU: CAY10006972-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10006972-1
• Package Unit: 1 mg
• Quantity Unit: STK