Ambenonium (chloride) (Standard), CAS 115-79-7

Ambenonium (chloride) (Standard), CAS 115-79-7
SKU
MEXHY-100919R-0
Packaging Unit
Get quote
Manufacturer
MedChemExpress

Availability: loading...
Price is loading...
Product Description: Ambenonium (chloride) (Standard) is the analytical standard of Ambenonium (chloride). This product is intended for research and analytical applications. Ambenonium (WIN 8077) chloride is an orally active and reversible inhibitor of Acetyicholinesterase (AChE) with high affinity. Ambenonium chloride inhibits human AChE with an IC50 value of 0.7 nM (hAChE)[1][2].

Formula: C28H42Cl4N4O2

References: [1]Hodge AS, et al. Ambenonium is a rapidly reversible noncovalent inhibitor of acetylcholinesterase, with one of the highest known affinities. Mol Pharmacol. 1992 May. 41(5):937-42./[2]Komloova M, et al. Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment. Bioorg Med Chem Lett. 2011 Apr 15. 21(8):2505-9./[3]Hazama R, et al. Effects of long-term administration of ambenonium chloride on motor end-plate fine structure and acetylcholine receptor in rat. J Neurol Sci. 1981 Jul. 51(1):69-79.

CAS Number: 115-79-7

Molecular Weight: 608.47

Research Area: Others

Target: Cholinesterase (ChE);Reference Standards
More Information
SKU MEXHY-100919R-0
Manufacturer MedChemExpress
Manufacturer SKU HY-100919R-0
Package Unit Get quote
Quantity Unit STK
Product information (PDF)
×
MSDS (PDF)
×