AMG 517 (Standard), CAS 659730-32-2

Product Description: AMG 517 (Standard) is the analytical standard of AMG 517. This product is intended for research and analytical applications. AMG 517 is a potent and selective vanilloid receptor-1 (TRPV1) antagonist with an IC50 of 0.5 nM.

Formula: C20H13F3N4O2S

References: [1]Doherty EM, et al. Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate. J Med Chem. 2007 Jul 26;50(15):3515-27./[2]Gavva NR, et al. Repeated administration of vanilloid receptor TRPV1 antagonists attenuates hyperthermia elicited by TRPV1 blockade. J Pharmacol Exp Ther. 2007 Oct;323(1):128-37.

CAS Number: 659730-32-2

Molecular Weight: 430.40

Research Area: Neurological Disease

Target: Reference Standards;TRP Channel

• SKU: MEXHY-10634R-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10634R-0
• Package Unit: Get quote
• Quantity Unit: STK