AMG-Tie2-1, CAS 870223-96-4

Product Description: AMG-Tie2-1 is an inhibitor of tunica interna endothelial cell kinase 2 (Tie2) with an IC50 of 1 nM. AMG-Tie2-1 is a VEGFR2 inhibitor with an IC50 of 3 nM[1].

Applications: Cancer-Kinase/protease

Formula: C25H20F3N5O2

References: [1]Brian L Hodous, et al. Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor. J Med Chem. 2007 Feb 22;50(4):611-26.

CAS Number: 870223-96-4

Molecular Weight: 479.45

Compound Purity: 99.5

Research Area: Cancer

Solubility: DMSO : 175 mg/mL (ultrasonic)

Target: VEGFR

• SKU: MEXHY-13023-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13023-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK