Aminopterin, CAS 54-62-6

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[4-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid

Purity: ≥95%

Formula Markup: C19H20N8O5

Formula Weight: 440.4

CAS Number: 54-62-6

Notes: Aminopterin is a synthetic folic acid (Item No. 20515) derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase, which is a cofactor for nucleic acid synthesis. Aminopterin has anticancer and immunosuppressive properties. Formulations containing it have been used for pediatric leukemia though methotrexate (Item No. 13960) is now more commonly used due to a more favorable therapeutic index.{34057,34058,34056} Aminopterin is a component of the widely used HAT (hypoxanthine-aminopterin-thymidine) medium to select cells for mammalian cell culture.{34059}

• SKU: CAY21802-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21802-10
• Package Unit: 10 mg
• Quantity Unit: STK