Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (2S,5R,6R)-6-[[(2R)-2-amino-2-(phenyl-2,3,4,5,6-d5)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Purity: ≥99% deuterated forms (d1-d5)
Formula Markup: C16H14D5N3O4S
Formula Weight: 354.43618
CAS Number: 1426173-65-0
Notes: Ampicillin-d5 is intended for use as an internal standard for the quantification of ampicillin (Item No. 14417) by GC- or LC-MS. Ampicillin is a broad-spectrum antibiotic with activity against Gram-positive and Gram-negative bacteria, including veterinary isolates of S. pseudintermedius, S. aureus, E. coli, Pasteurella, and S. canis (MIC50s = 0.25, 0.5, 2, 0.12, and 0.25 μg/ml, respectively).{39898} In vivo, ampicillin (80 mg/kg, i.v.) reduces cough frequency, tachypnea, dyspnea, and fever and increases survival in a baboon (P. cynocephalus) model of pneumococcal pneumonia.{39899} Formulations containing ampicillin have been used to treat a variety of bacterial infections.
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