Product Description: AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). AN3661 inhibits Plasmodium falciparum laboratory-adapted strains (mean IC50=32 nM), Ugandan field isolates (mean ex vivo IC50=64 nM), and murine P. berghei and P. falciparum infections[1].
Applications: COVID-19-immunoregulation
Formula: C10H11BO4
References: [1]Sonoiki E, et al. A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue. Nat Commun. 2017;8:14574. Published 2017 Mar 6.
CAS Number: 1268335-33-6
Molecular Weight: 206.00
Compound Purity: 99.89
Research Area: Infection
Solubility: DMSO : 250 mg/mL (ultrasonic)
Target: Parasite