Ankyrin G Antibody, Clone N106/20: APC

Mouse Anti-Human Ankyrin G Monoclonal IgG1

Target: Ankyrin G

Conjugate: APC

Product Type: Monoclonal

Clone Number: N106/20 (Formerly sold as S106-20)

Immunogen: Fusion protein 1000 C-terminal amino acids of human Ankyrin G (also known as ANK-3 or ankyrin-3) encompassing all of Ankyrin G with the exception of Ankyrin repeats

Swiss-Prot: Q12955

Purification: Protein G Purified

Storage Buffer: 95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Concentration: 1 mg/ml

Specificity: Detects >~200kDa.

Cellular Localization: Cytoplasm / Cytoskeleton / Cell Projection / Axon / Cell Membrane / Sarcolemma / Cell Junction / Synapse / Postsynaptic Cell Membrane / Lysosome

Scientific Background: Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane.

References: 1. Bennett V., Baines A.J. (2001) Physiol. Rev. 81 (3): 1353–92.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSMC-404D-APC
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SMC-404D-APC
• Package Unit: 100 µg
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Monoclonal
• Application: Immunofluorescence, Immunohistochemistry, Immunocytochemistry
• Isotype: IgG1
• Human Gene ID: 288
• Host: Mouse
• Conjugate: Conjugated, APC (Allophycocyanin)