Antigen Long Description: 4-(2-carboxyethylthio)-11-deoxycortisol linked to bovine serum albumin.
Origin Pub PMID: 1922102
Buffer Composition: PBS only.
Specificity Statement: Binds specifically to 11-deoxycortisol. No cross-reactivity with cortisol or cortisone.
Application Notes (Clone): The antibody binds specifically to 11-Deoxycortisol, a glucocorticoid steroid hormone which can be oxygenated to cortisol. The monoclonal antibody recognises the functional groups at C-11 and C-21 in the steroid portion of 11-deoxycortisol, and can be useful in determining plasma levels of deoxycortisol in the metyrapone test in the diagnosis of Cushing's syndrome and adrenal insufficiency.