CloneID: m86
Antigen Long Description: Rabbit red cells, on which α-gal is the major carbohydrate epitope, were injected into alpha 1,3 galactosyltransferase knock-out mice.
Origin Pub PMID: 11090880
Buffer Composition: PBS only.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgM format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody binds to the alpha-gal epitope on glycoproteins and glycolipids.
Application Notes (Clone): This antibody binds to the alpha-gal epitope found on many glycoproteins and glycolipids of non-primate mammalis, prosimians and New World monkeys. Antibodies agains the alpha-gal epitopes occur naturally in Old World monkeys, apes and humans, and induce xenograft rejection from non-primate animals.
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