Anti-Alpha-Synuclein (NAC32)

Anti-Alpha-Synuclein [NAC32], Recombinant, IgG1 kappa, Human

CloneID: NAC32

Heavy Chain modification: Fc Silent™

Antigen Long Description: Biotin-labeled peptide spanning amino acids 53-87 of alpha-synuclein.

Origin Pub PMID: 18237741

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: P37840

Specificity Statement: Binds the nonamyloid component of alpha-Synuclein.

Application Notes (Clone): This is a synthetic IgG binding to alpha-Synuclein which is involved in the regulation of dopamine release and transport. It induces fibrillisation of the tau-protein and reduces the neuronal responsiveness to several apoptotic signals. Involved in the pathogenesis of Parkinson disease.

• SKU: ABAAb00346-10.3
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00346-10.3
• Package Unit: 200 μg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Western Blotting, Immunohistochemistry, Blocking
• Isotype: IgG1 kappa
• Host: Human