Anti-Apolipoprotein B-100 (MabB9)

Anti-Apolipoprotein B-100 [MabB9], Recombinant, IgG2b kappa, Mouse

CloneID: MabB9

Antigen Long Description: The original antibody was generated by immunizing female BALB/c mice intraperitoneally with 20ug of human apo B-100 and dead Salmonella microbes.

Buffer Composition: PBS only.

Uniprot Accession No.: P04114

Specificity Statement: This antibody binds human apolipoprotein B (APOB). Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. It is involved in the metabolism of lipids and is the main protein constituent of lipoproteins such as very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL, the “bad cholesterol”).

Application Notes (Clone): The binding characterization of this antibody towards human APO-B was done using ELISA and immunoblotting. This antibody was also used in a serum assay to determine the quantity of apo-B in a sample using competitive ELISA. This antibody was shown to react with isolated human Apo-B as well as low density lipids but not with high density lipids and lipoprotein-deficient serum (Yoon et al., 1993).

• SKU: ABAAb03939-3.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab03939-3.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Western Blotting, ELISA
• Isotype: IgG2b kappa
• Host: Mouse