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Assay Conditions: See datasheet for detailed information
Cross Reactivity: This antibody recognizes human BCMA. It has not been tested with other species.
Description: This anti-BCMA antibody is a purified, biotinylated, recombinant human monoclonal antibody which recognizes the human BCMA protein. BCMA is also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17) and is expressed on the surface of plasma cells. BCMA is important for plasma cell differentiation and B cell proliferation. BCMA is a validated therapeutic target in multiple myeloma. The first anti-BCMA CAR-T cell therapy (idecabt agene vicleucel) was approved by the FDA in 2021.
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, 20% glycerol
Purification: Protein A affinity chromatography from HEK293 supernatants
Purity: ≥90%
Storage Stability: At least 12 months at -80°C.
Uniprot: Q02223
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
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