Anti-BMP receptor type IA (AbD1556)

Anti-BMP receptor type IA [AbD1556], Recombinant, IgG1 lambda, Mouse

CloneID: AbD1556

Antigen Long Description: Biotinylated BMPR-IA immobilized on a resin.

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric mouse antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P36894

Specificity Statement: The antibody binds to human BMPR-IA with a low nanomolar affinity.

Application Notes (Clone): This antibody binds to human BMPR-1A, which, on ligand bindingg, forms a receptor complex acting as a serine/threonine kinase, activating SMAD transcriptional regulators. They positively regulate chondrocyte differentiation, for example. The antibody neutralizes BMP-binding to the receptor.

• SKU: ABAAb00426-1.1-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00426-1.1-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: ELISA, Blocking, Super-Resolution Microscopy
• Isotype: IgG1 lambda
• Host: Mouse