CloneID: BAG2
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was isolated from a semi-synthetic phage display library of humanized Fab fragments, by panning against BRIL.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human Fab format, created for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P0ABE7
Specificity Statement: The antibody is specific for BRIL.
Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis. The crystal structure of the antibody in complex with BRIL was determined by cryoEM (Mukherjee et al., 2020; PMID: 32221310).
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