CloneID: 4A6
Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with carbohydrate antigen 19-9.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Specificity Statement: This antibody binds CA19-9, which is a mucin-type glycoprotein tumor marker, a glycolipid on the cell membrane. It is known to play a role in cell-to-cell recognition processes. Elevated levels of CA 19-9 may indicate advanced cancer in the pancreas, but it is also associated with noncancerous conditions, including gallstones, pancreatitis, cirrhosis of the liver, and cholecystitis.
Application Notes (Clone): This antibody was used in a double antibody sandwich ELISA where antibody 4A6 is a capture antibody, and the antibody 4G2 is a detection antibody. The detection method had high sensitivity, with the LOD of CA19-9 detection as 21.333ng/mL (CN114573700).
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