Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original mouse IgG1 format for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: Binds to human CCL2.
Application Notes (Clone): This antibody binds to human CCL2, a small cytokine that recruits monocytes, memory T cells and dendritic cells to the sites of inflammation. Can block monocyte chemotaxis in cell migration assays (PMID: 15967845)