Anti-CD11a (hu1124 (Efalizumab))

Anti-CD11a [hu1124 (Efalizumab)], Recombinant, IgG2a kappa, Mouse

CloneID: hu1124 (Efalizumab)

Antigen Long Description: Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.

Buffer Composition: PBS with 0.02% Proclin 300.

Chimeric Use Statement: This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: P20701

Specificity Statement: Binds to human LFA-1.

Application Notes (Clone): Efalizumab binds to the LFA-1 alpha I domain blocking the ICAM-1 binding site via steric hindrance.

• SKU: ABAAb00535-2.0
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00535-2.0
• Package Unit: 200 μg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Flow Cytometry, Blocking
• Isotype: IgG2a kappa
• Host: Mouse