Anti-CD11a (hu1124 (Efalizumab))

Anti-CD11a [hu1124 (Efalizumab)], Recombinant, IgG2a kappa, Mouse

CloneID: hu1124 (Efalizumab)

Antigen Long Description: Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P20701

Specificity Statement: Binds to human LFA-1.

Application Notes (Clone): Efalizumab binds to the LFA-1 alpha I domain blocking the ICAM-1 binding site via steric hindrance.

• SKU: ABAAb00535-2.0-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00535-2.0-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Flow Cytometry, Blocking
• Isotype: IgG2a kappa
• Host: Mouse