Anti-CD134 (OX-40)

Anti-CD134 [OX-40], Recombinant, IgG2b kappa, Rat

CloneID: OX-40

Heavy Chain modification: Fc Silent™

Antigen Long Description: OX40 antibody was prepared by immunizing mice with phytohaemagglutinin-activated rat lymph node cells.

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P15725

Specificity Statement: OX-40 antibody binds specifically to CD4+ T blasts. CD134 is a protein of the TNFR superfamily. It binds to OX40 ligand of both the monomeric and trimeric states which results in co-stimulated proliferation.

Application Notes (Clone): OX-40 antibody results in Fc-dependent (i.e. not Fab or F(ab')2) stimulation of in vitro activated T cell proliferation, but is not mitogenic for resting cells. This antibody can also label CD4+ T blasts and can pull down CD134/CD134+ cells.

• SKU: ABAAb00547-8.4-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00547-8.4-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Rat (Rattus)
• Clonality: Recombinant
• Application: Immunohistochemistry (frozen), Immunoprecipitation, Flow Cytometry, Functional Assay, Fluorescence-Activated Cell Sorting (FACS)
• Isotype: IgG2b kappa
• Host: Rat