Anti-CD147 (059-053)

Anti-CD147 [059-053], Recombinant, IgG lambda, Rabbit

CloneID: 059-053

Antigen Long Description: The original antibody was isolated by panning a phage display library against CD147.

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: P35613

Specificity Statement: The antibody is specific for CD147. CD147 acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. Further, in association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors.

Application Notes (Clone): The IgG1 format of the antibody specifically bound to the cancer cells expressing CD147 (CCF-RC1, ACHN) and expresses the ADCC activity (US9388249B2).

• SKU: ABAAb04151-23.0
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab04151-23.0
• Package Unit: 100 μg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Antibody-Dependent Cell-mediated Cytotoxicity (ADCC)
• Isotype: IgG lambda
• Host: Rabbit