Anti-CD2 (OX-34)

Anti-CD2 [OX-34], Recombinant, IgG2b kappa, Rat
SKU
ABAAb00559-8.1-BT
Packaging Unit
1 mg
Manufacturer
Absolute Antibody

Availability: loading...
Price is loading...
CloneID: OX-34

Antigen Long Description: OX-34 was prepared by immunizing mice with T blasts prepared inmixed lymphocyte reactions with purified rat T helper cells against irradiated spleen.

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P08921

Specificity Statement: OX-34 binds specifically to rat CD2. CD2 is type I membrane protein involved in triggering of T-cells (cytoplasmic domain is involved in signaling function) and is expressed on thymocytes, peripheral T cells, dendritic epidermal T cells, macrophages in the spleen, and NK cells.

Application Notes (Clone): Ox34 blocks CD48 binding to CD2 causing partial block of T cell activation; OX34 can be used to deplete peripheral T cells (used to prevent allograft rejection in vivo).
More Information
SKU ABAAb00559-8.1-BT
Manufacturer Absolute Antibody
Manufacturer SKU Ab00559-8.1-BT
Package Unit 1 mg
Quantity Unit STK
Reactivity Rat (Rattus)
Clonality Recombinant
Application Flow Cytometry, Blocking
Isotype IgG2b kappa
Host Rat
Product information (PDF) Download
MSDS (PDF) Download