Antigen Long Description: OX-110 was generated from rats using immunogenic mouse fusion protein mCD200RCD4d34.
Buffer Composition: PBS only.
Uniprot Accession No.: Q9ES57
Specificity Statement: OX-110 binds specifically to CD200R proteins. CD200R is a type I membrane protein and an inhibitory receptor for the CD200/OX-2 cell surface glycoportein. CD200R acts to limit inflammation by inhibiting expression of pro-inflammatory molecules such as TNF-alpha, interferons and iNOS in response to selected stimuli. CD200R is expressed on rodent myeloid cells and is involved in regulation of macrophage function.
Application Notes (Clone): OX-110 can be used to stain in FC.