Anti-CD26 (OX-61)

Anti-CD26 [OX-61], Recombinant, IgG2b kappa, Rat

CloneID: OX-61

Heavy Chain modification: Fc Silent™

Antigen Long Description: OX-61 was prepared by immunizing mice with rat thoracic duct lymphoid cells that were enriched for dendritic cells.

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P14740

Specificity Statement: OX-61 binds specifically to DPP4. Evidence: tissue distribution of OX-61 and DPP4 are identical; equal MWTs; OX-61-mediated reduction in DPP4 activity from solubilized liver homogenates. DPP4 is a glycoprotein receptor which acts as a positive regulator of T cell co-activation.

Application Notes (Clone): This antibody can be used for denaturing and non-denaturing WB and developed using peroxidase-conjugated rabbit anti-mouse. It can also be used for IHC of cryostat sections from adult rat liver. Staining is also observed on the brush border of the small intestine and colonic epithelium, T cell areas of lymphoid cells but not B cell follicles

• SKU: ABAAb00568-8.4-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00568-8.4-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Rat (Rattus)
• Clonality: Recombinant
• Application: Immunofluorescence, Immunoprecipitation, Western Blotting, Flow Cytometry, Immunohistochemistry, Radioimmunoassay (RIA), Immunocytochemistry
• Isotype: IgG2b kappa
• Host: Rat