Anti-CD33 (hP67.6 (Gemtuzumab)), Human IgG4, CONJUmAb™, kappa

CloneID: hP67.6 (Gemtuzumab)

Heavy Chain modification: CONJUmAb™

Antigen Long Description: Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.

Buffer Composition: PBS only

Uniprot Accession No.: P20138

Specificity Statement: Recognises human CD33.

Application Notes (Clone): A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.

• SKU: ABAAb00283-13.0CM-CMV
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00283-13.0CM-CMV
• Package Unit: 5 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Immunofluorescence, Flow Cytometry
• Isotype: IgG4 kappa
• Host: Human