Anti-CD43 (OX-58)

Anti-CD43 [OX-58], Recombinant, IgG2b kappa, Rat
SKU
ABAAb00586-8.4
Packaging Unit
200 μg
Manufacturer
Absolute Antibody

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CloneID: OX-58

Heavy Chain modification: Fc Silent™

Antigen Long Description: This antibody was prepared by immunizing BALB/c mice with rat thymocyte leukosialin and thymocytes.

Buffer Composition: PBS with 0.02% Proclin 300.

Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: P13838

Specificity Statement: This antibody recognises rat leukosialin, a major cell-surface sialoglycoprotein of thymocytes and T lymphocytes. It is also expressed on neutrophils, bone marrow stem cells and B-lineage cells after activation. The specificity of the leukosialin epitope is largely determined by linear protein sequence, as indicated by the reaction of this antibody with the extracellular domain of leukosialian expressed in an unglycosylated form in E. coli. However, the sensitivity of this antibody to neuraminidase treatment of leukosialin indicates that glycosylation can modify epitope conformation or flexibility.

Application Notes (Clone): This antibody binds to rat leukosialin, and can be used to label thymocytes and T lymphocytes in the lymph node cell population in flow cytometry analysis. This antibody has also been used, along with other anti-CD43 MABs, in a Western blot analysis to localize leukosialin epitopes.
More Information
SKU ABAAb00586-8.4
Manufacturer Absolute Antibody
Manufacturer SKU Ab00586-8.4
Package Unit 200 μg
Quantity Unit STK
Reactivity Rat (Rattus)
Clonality Recombinant
Application Western Blotting, Flow Cytometry, Radioimmunoassay (RIA)
Isotype IgG2b kappa
Host Rat
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