Anti-CD45RC (OX-22)

Anti-CD45RC [OX-22], Recombinant, IgG1 kappa, Mouse
SKU
ABAAb00562-1.1-BT
Packaging Unit
1 mg
Manufacturer
Absolute Antibody

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CloneID: OX-22

Antigen Long Description: OX-22 was prepared by immunizing BALB/c mice with phytohemagglutinin-activated rat lymph node cells.

Buffer Composition: PBS only.

Uniprot Accession No.: P04157

Specificity Statement: OX-22 binds specifically to the high molecular weight form of the leucocyte common antigen, CD45RC. OX-22 and OX-31 compete for binding but do not compete with OX-32. The antigen is expresssed on the surface of B cells, around half of bone marrow cells, all CD8+ve T cells, and is able to differentiate between CD4+CD45RChigh (Th1-like) and CD4+CD45RClow (Th2-like) cell types. CD45 extracellular domain is able to interact with a number of different proteins including CD4, TCR, CD2, Thy-1 and CD26. CD45 is important for signalling throguh the T cell receptor and in the selection of T and B lymphocytes.

Application Notes (Clone): OX-20 can be used for both FC and IHC (paraffin/frozen) studies. It can also be used to purify proteins by affinty-purification (Woolett et al. Eur J Immunol. 1985 Feb;15(2):168-73).
More Information
SKU ABAAb00562-1.1-BT
Manufacturer Absolute Antibody
Manufacturer SKU Ab00562-1.1-BT
Package Unit 1 mg
Quantity Unit STK
Reactivity Rat (Rattus)
Clonality Recombinant
Application Immunoprecipitation, Flow Cytometry, Immunohistochemistry
Isotype IgG1 kappa
Host Mouse
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