CloneID: OX-19
Heavy Chain modification: Fc Silent™
Antigen Long Description: Rat immunized with thymocyte glycoproteins.
Buffer Composition: PBS only.
Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P51882
Specificity Statement: This antibody binds to CD5 glycoprotein primarily expressed on thymocytes and mature peripheral T lymphocytes. CD5 is a member of the scavenger receptor superfamily and primarily expressed on thymocytes and mature peripheral T lymphocytes, but not on NK cells, intestinal intraepithelial gamma/delta T cells.
Application Notes (Clone): This antibody can be used for denaturing and non-denaturing WB and developed using peroxidase-conjugated rabbit anti-mouse. It can also be used for IHC of cryostat sections from adult rat liver. Staining is also observed on the brush border of the small intestine and colonic epithelium, T cell areas of lymphoid cells but not B cell follicles