CloneID: 33A2
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing mice with CD56.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P13591
Specificity Statement: The antibody is specific for CD56. CD56 is a 140KD glycoprotein expressed on the cell surface, is a member of the immunoglobulin superfamily, belongs to the NCAM subtype.CD56 protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
Application Notes (Clone): The antibody 33A2 and the commercial antibody 56C04 were used to stain small cell lung cancer and brain tissue. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 33A2 was higher than the commercial antibody. The antibody and the commercially available antibody 56C04 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN113831410A).
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