Anti-CD6 (OX-126)

Anti-CD6 [OX-126], Recombinant, IgG1 kappa, Human

CloneID: OX-126

Heavy Chain modification: Fc Silent™

Antigen Long Description: This antibody was raised by immunizing BALB/c mice with a fusion protein consisting of human CD6 domain 3 and rat CD4 domains 3 and 4 (CD6d3CD4d3 + 4) (corrected, see: (Hassan et al., 2019; pmid: 30890626)).

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P30203

Specificity Statement: This antibody is specific for the domain 2 of human CD6. Binding depends on a SNP ( R, amino acid 225).

Application Notes (Clone): This antibody is noncompetitive with OX125 and does not block CD6/CD166 interactions (Santos et al., 2019; pmid: 31162836).

• SKU: ABAAb00539-10.3-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00539-10.3-BT
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Recombinant
• Application: Flow Cytometry
• Isotype: IgG1 kappa
• Host: Human