Anti-CD6 (OX-126)

Anti-CD6 [OX-126], Recombinant, IgG1 kappa, Human
SKU
ABAAb00539-10.3-BT
Packaging Unit
1 mg
Manufacturer
Absolute Antibody

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CloneID: OX-126

Heavy Chain modification: Fc Silent™

Antigen Long Description: This antibody was raised by immunizing BALB/c mice with a fusion protein consisting of human CD6 domain 3 and rat CD4 domains 3 and 4 (CD6d3CD4d3 + 4) (corrected, see: (Hassan et al., 2019; pmid: 30890626)).

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P30203

Specificity Statement: This antibody is specific for the domain 2 of human CD6. Binding depends on a SNP ( R, amino acid 225).

Application Notes (Clone): This antibody is noncompetitive with OX125 and does not block CD6/CD166 interactions (Santos et al., 2019; pmid: 31162836).
More Information
SKU ABAAb00539-10.3-BT
Manufacturer Absolute Antibody
Manufacturer SKU Ab00539-10.3-BT
Package Unit 1 mg
Quantity Unit STK
Reactivity Human
Clonality Recombinant
Application Flow Cytometry
Isotype IgG1 kappa
Host Human
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