CloneID: OX-126
Antigen Long Description: This antibody was raised by immunizing BALB/c mice with a fusion protein consisting of human CD6 domain 3 and rat CD4 domains 3 and 4 (CD6d3CD4d3 + 4) (corrected, see: (Hassan et al., 2019; pmid: 30890626)).
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P30203
Specificity Statement: This antibody is specific for the domain 2 of human CD6. Binding depends on a SNP ( R, amino acid 225).
Application Notes (Clone): This antibody is noncompetitive with OX125 and does not block CD6/CD166 interactions (Santos et al., 2019; pmid: 31162836).
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